Best-rated hotels in Muscatine for your unforgettable stay

Detailed descriptions, travelers’ reviews, and handpicked hotel collections will help you book your perfect accommodation.

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Choose from exclusive hotel collection

We offer thousands of Muscatine hotels and accommodations from world's renowned hotel chains to unique gems of the region you won’t find anywhere else.

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Once you choose your best place to stay, take a minute to complete a quick reservation form and get an instant confirmation letter to your email address.

Benefit from flexible travel options

We provide the most flexible cancellation options, so you get your deposit back in case of a change of plans or other unforeseen circumstances.

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Hotels by class
2 stars 3
Unrated 1
Thematic Hotels
Pet-friendly hotels 8
Luxury accommodations 7
Golf hotels 7
Business hotels 5
Hotels with indoor pool 4
Exceptional design hotels 3
Boutique hotels 1
Ski resorts 1
Luxury hotels 1
Self Catering 1
Beach hotels 1
Sustainability certification 1
Jacuzzi 1

Hotels by location

Nearby
Weed Park Maintenance 9
Pearl Button Museum 10
Muscatine Kent-Stein Park 10
Fireman's Hall Muscatine 3
Muscatine Park and Recreation 10
Muscatine City Parks and Rec 10
Fellowship Hall and Custodian Muscatine 10
Muscatine Community College 10
Kent-Stein Park 10
Landmarks
Museums
Parks
Landmark
Popular attractions

Welcome to Muscatine

Muscatine, Iowa offers a delightful blend of history and nature. Explore the charming riverfront with its stunning views of the Mississippi River. Immerse yourself in the rich heritage of this vibrant city through its museums and historical landmarks. Discover delightful parks and trails, perfect for leisurely strolls or outdoor activities. Experience small-town charm with a visit to local shops and restaurants. Come and uncover the hidden gems of Muscatine.

What our users say about Muscatine hotels

9.8

Exceptional

us Thomas 27 April 2022
Booked a room with a nice decoration. Rewritten: I reserved a room with lovely decor.
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9.4

Excellent

us Natalie 23 May 2021
Caring staff, reasonably large and large room, perfect location. We had a continental breakfast which was satisfactory. Generally the service was outstanding.
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9.8

Exceptional

us Diana 09 October 2022
This place was pretty good for a 4-star hotel, and I really enjoyed my stay here. The location was amazing, just a quick 5-minute walk to the Heritage Museums. 🏛️
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7.8

Good

us Brett 08 January 2021
Great stay in this hotel. This venue had everything we needed, we enjoyed staff and the food. The restaurant was perfect for breakfast.
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9.0

Good

us Robert 23 October 2019
Convenient base for a trip in Des Moines! Centro Restaurant was 10 mins walk away. No reason to complain with the hotel...
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9.2

Excellent

us Katherine 15 April 2021
It was worth its 4 stars. Private bathroom with all essentials. The GOOD restaurant is a nice plus.
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9.4

Excellent

us Steve 08 July 2020
The location was great and the staff was pleasant. It was right by Pond for Growth. Besides, Wi Fi worked pretty fast.
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9.4

Excellent

us Henry 29 June 2022
The staff was courteous and welcoming throughout my stay. The rooms were well-maintained and had free Wi-Fi, mini-fridge, and microwave. The location was convenient to nearby attractions and businesses, allowing me to hit some great spots. Plus, the hotel offered a complimentary breakfast bar and coffee, which was convenient for my early morning departure.
Despite the positives, there were a few cons. The bed was not made daily and the room service only tended to the bare minimum.
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7.4

Good

us James 28 August 2022
During my Thanksgiving stay, I enjoyed the complimentary breakfast and the free wifi, which made my stay even more comfortable. Additionally, the hotel's location was very convenient, with easy access to nearby attractions and restaurants.
The room did not meet my expectations in terms of cleanliness. The room's bathroom tiles were broken, and the bathtub looked dirty, which was a bit disappointing.
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Save time on your trip arrangements by booking one of our hand-picked hotels

Top 5-star hotels
Best 4-star hotels
Exclusive 3-star hotels
Quality 2-star hotels
Indulge yourself with luxury and comfort as you explore the exciting attractions of Muscatine.
Strawberry Farm B And B

3402 Tipton Road, Muscatine, United States

Excellent
25 reviews

147 US$

min. price/night

Experience the best value for your money by checking out our selection of 4-star Muscatine hotels.
The Merrill Hotel & Conference Center, Muscatine, A Tribute Portfolio Hotel

119 West Mississippi Drive, Muscatine, United States

Excellent
55 reviews

134 US$

min. price/night

Enjoy truly authentic experiences without compromising comfort and convenience.
Best Western Muscatine - Pearl City Hotel

305 Cleveland Street, Muscatine, United States

Good
134 reviews

82 US$

min. price/night

Americinn By Wyndham Muscatine

3115 N Highway 61, Muscatine, United States

Good
100 reviews

95 US$

min. price/night

Hampton Inn Muscatine

3303 North Port Drive, Muscatine, United States

Good
37 reviews

124 US$

min. price/night

Hotel Muscatine

2915 N Highway 61, Muscatine, United States

59 US$

min. price/night

Discover the hidden gems of Muscatine by booking one of its budget-friendly hotels.
Comfort Inn Muscatine Near Hwy 61

115 Cleveland Street, Muscatine, United States

Good
63 reviews

110 US$

min. price/night

Super 8 By Wyndham Muscatine Hotel

2900 North Highway 61, Muscatine, United States

Good
49 reviews

68 US$

min. price/night

Travelodge Inn & Suites By Wyndham Muscatine

2402 Park Avenue, Muscatine, United States

50 US$

min. price/night

Travelers’ choice

Check out the most booked accommodations to find reliable places that our users have tried and tested.
The Sage Hotel

2402 Park Avenue, Muscatine, United States

Good
26 reviews

54 US$

min. price/night

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